Vaccines During Pregnancy: Tdap, Flu, RSV, and COVID — What Is Recommended

A clear guide to pregnancy vaccines recommended by CDC and ACOG — timing, safety, and how they protect your newborn.

Vaccines in pregnancy protect two people at once: you and your baby, who receives protective antibodies through the placenta and breast milk. Recommendations evolve as new data emerges — always confirm current guidance with your provider.

Influenza (flu) vaccine

Recommended in any trimester during flu season. Pregnant people are at higher risk of severe flu complications. The inactivated injectable flu vaccine is safe; avoid the nasal live vaccine in pregnancy.

Tdap (whooping cough)

Given between 27 and 36 weeks in each pregnancy, regardless of prior vaccination. It is the most effective way to protect newborns from pertussis before they can be vaccinated themselves at 2 months.

RSV and COVID-19

RSV monoclonal antibody for infants or maternal RSV vaccination may be offered depending on season and guidelines in your country. COVID-19 vaccination is recommended — pregnancy increases severe illness risk. Discuss timing and specific products with your care team.

What to avoid

Live attenuated vaccines (like MMR and varicella) are generally deferred until after delivery unless you are non-immune and exposure risk is high — your provider will weigh risks and benefits.